Her death was announced toThe New York Timesby her father, the entertainment lawyer Hal Friedman.

Both the series and Friedmans storyline were revolutionary in both casting and fully-rounded depictions of people with the syndrome.

The line was a clear reference to Palin, whose son Trig has Down syndrome.

Actress, Andrea Fay Friedman attend the International Film Festival and Forum at the ArcLight, Media Forum July 27, 2003 in Hollywood, California.

Andrea Fay Friedman (2003)Chris Hatcher/Getty Images

Palin went on Fox News to condemn the episode, calling all those involved cruel, cold-hearted people.

My parents raised me to have a sense of humor and to live a normal life.

Outside her acting career, Friedman worked with U.C.L.A.s Pathway program for students with intellectual disabilities.

Bleecker Street Media CEO Andrew Karpen dead