The 28,000-square-foot space, across two floors at 1 Newman Street, is situated between Fitzrovia and Soho.
The initial head-count will be around 100.
UTAs new London office will continue to be co-led by music agents Neil Warnock and Obi Asika.

David KramerCourtesy
We watched some of our competitors send film and TV agents to London and we learnt from that.
It wasnt always received well.
When we bought CBG we didnt want it to feel like the Americans were coming in over the wall.

Weve taken the approach of having agents go to London and embed themselves and spend some time there.
There is so much international talent and so many international buyers in Europe now.
Film, TV and production agents will be part of our full suite of staff in London over time.
U.S. agencies have been kicking the tyres on potential UK agency acquisitions in recent years.
Independent is among those often speculated about for a sale or significant new investment.
UTA made the first big splash by acquiring Curtis Brown.
Kramer said the cultural and practical mesh with the respected UK firm had been great.
Weve stuck to the plan.
It has been nice to see how both communities have responded to it.
The UK was the most logical first step.
There are a lot of other places we would like to tap into given the proliferation of global content.
UTA first established a presence in London with its 2015 acquisition of UK music company The Agency Group.
The firm is headquartered in LA and also has offices in Atlanta, Chicago, Nashville and New York.
Were hopeful the business will get back to its previous volume soon after this is resolved.